Histologic chorioamnionitis occurs in approximately 50–60% of women with preterm premature rupture of membranes
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چکیده
Histologic chorioamnionitis occurs in approximately 50–60% of women with preterm premature rupture of membranes (PPROM). This condition is thought to represent antenatal inflammation/infection, which contributes to impending preterm birth and neonatal sepsis, chronic lung disease, and brain injury. Early and accurate diagnosis of chorioamnionitis is important, although it is limited by the fact that placental pathology cannot be evaluated before delivery. Several studies have attempted to identify rapid yet highly sensitive and specific diagnostic markers for diagnosing chorioamnionitis by analyzing factors in amniotic fluid (AF) obtained during amniocentesis, such as AF interleukin-6 (IL-6): this parameter has been reported as a significant predictor. However, amniocentesis is an invasive procedure with accompanying risks, and a decreased AF volume in cases of PPROM often makes it Non-Invasive Prediction of Histologic Chorioamnionitis in Women with Preterm Premature Rupture of Membranes
منابع مشابه
Predictive Values of Maternal Serum Levels of Procalcitonin, ESR, CRP, and WBC in the Diagnosis of Chorioamnionitis in Mothers with Preterm Premature Rupture of Membrane
Background: Premature rupture of membrane (PROM) refers to the rupture of fetal membranes at least 1 hour before the onset of labor pain. We aimed to determine the predictive value of maternal serum level of procalcitonin in the early diagnosis of chorioamnionitis in mothers with preterm (PPROM).Methods: In this prospective cohort study, 48 patients with PPROM were selected due to limited finan...
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Background & Aims: Preterm premature rupture of membranes (PPROM) is the leading cause of preterm birth and perinatal mortality and morbidity, and complications. The objective of the present study was to assess the effect of progesterone agents (rectal suppositories and weekly injection of 17- hydroxyprogesterone caproate) on latency period in women with PPROM. Methods: This randomized, double-...
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